Cialis, also known as tadalafil, is a medication primarily used to treat erectile dysfunction (ED). It belongs to a class of drugs known as phosphodiesterase type 5 (PDE5) inhibitors. Cialis works by helping to increase blood flow to the penis, enabling men to achieve and maintain an erection. It may also be used to treat benign prostatic hyperplasia (BPH) and pulmonary arterial hypertension (PAH).
Cialis is used to treat erectile dysfunction (ED). It belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. It works by helping to increase blood flow to the penis, enabling men to achieve and maintain an erection. Cialis may also be prescribed for other purposes, such as to treat pulmonary arterial hypertension (PAH).
Cialis may also be used for purposes not listed in this medication guide.
Common side effects may include headache, flushing, indigestion, nasal congestion, dizziness, and back pain. It is important to avoid alcohol and grapefruit juice while taking Cialis. Contact your doctor or pharmacist if you have any concerns or questions about the side effects or about the use of Cialis.
For more information about Cialis, including its uses, see.
Before taking Cialis, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Cialis can interact with other medications and supplements. This is especially important if you are taking any of the following medications:
Cialis may also interact with certain other medications, including some antifungals, and supplements. Tell your health care provider about all the medications you are taking, including prescription and over-the-counter drugs, vitamins, and herbal products. This includes vitamins, supplements, and herbal products that contain substances that could interact with Cialis.
The typical starting dose of Cialis for erectile dysfunction (ED) is 10 mg taken about 30 minutes to 1 hour before sexual activity. Your doctor may adjust the dosage based on your response and other medications you may be taking. Depending on your response, your doctor may recommend a lower dose of the medication.
Cialis may be taken with or without food.
It is important to note that Cialis should not be taken with grapefruit or grapefruit juice. Grapefruit and grapefruit juice can affect how Cialis works and increase the risk of side effects. grapefruit products should not be taken more than once per day.
Cialis may cause side effects. However, these are not experienced by everyone and may vary from person to person. Common side effects of Cialis include headache, flushing, indigestion, nasal congestion, dizziness, and back pain. If any of these side effects become bothersome, contact your doctor.
If you experience any severe or persistent side effects, such as chest pain, chest discomfort, swelling, or trouble breathing, seek medical attention immediately.
The research on tadalafil (Cialis) was conducted at the National University of Otherwise Known Diseases (NUID), at NUID, from 2015 to 2021, and the National Cancer Institute of the National Institutes of Health (NIH), NUI. The current study investigated the impact of tadalafil on tadalafil-induced tadalafil-associated and tadalafil-dependent prostate-specific antigen (PSA) concentrations and PSA levels in mice. In addition, tadalafil (5 mg/kg) was administered to the rats to determine the effects of tadalafil on PSA and tadalafil-induced prostate-specific antigen (PSA). We previously reported that tadalafil, which is a PDE5 inhibitor, increased the PSA level by 1.6-fold and PSA by 0.8-fold in the prostate and bladder, respectively, in male rats. Our previous results showed that tadalafil, which was shown to have a similar effect on prostate-specific antigen (PSA) concentrations in mice but was less effective in the bladder, supported this finding. In this study, we evaluated the effect of tadalafil on tadalafil-induced PSA levels and PSA in vivo and on PSA and PSA-related factors in mice.
The results of the present study showed that tadalafil (5 mg/kg) was more effective in increasing PSA and PSA levels in the rat compared to the mouse, but the results in the prostate were not significant, and tadalafil was more effective in increasing PSA and PSA levels in the rat than the mouse. It is believed that tadalafil can inhibit PSA and PSA, which can be used to treat prostate-specific antigen (PSA) levels in patients with benign prostatic hyperplasia. In the present study, we observed that tadalafil improved PSA levels in the rat compared to the mouse, which was significantly higher than the mouse, but the mouse PSA was less than that of the rat.
To evaluate the effect of tadalafil on PSA levels in the rat, we first evaluated the effect of tadalafil on PSA and PSA-related factors, including tadalafil-induced PSA and PSA-related factors, in mice. Our previous studies showed that tadalafil increased PSA in the prostate but not in the bladder, suggesting that tadalafil has a similar effect on PSA levels in both the bladder and the prostate. To evaluate the effects of tadalafil on PSA levels in the rat, we administered tadalafil or a tadalafil-based treatment of the rat, which was administered the same dosage of tadalafil as the rat, and PSA levels were measured. In a previous study, we showed that tadalafil treatment decreased PSA and PSA-related factors in the rat, but not in the mouse. These results suggested that tadalafil improved PSA and PSA-related factors in the rat.
The present study was conducted to evaluate the effect of tadalafil on tadalafil-induced PSA levels and PSA-related factors in rats. Previous studies showed that tadalafil increased PSA in the rat, but PSA levels in the rat were not affected by tadalafil. In this study, we evaluated the effect of tadalafil on tadalafil-induced PSA levels and PSA-related factors in the rat. In addition, tadalafil increased PSA in the rat, but PSA levels were not affected by tadalafil. This may be because tadalafil was not a PDE5 inhibitor, which was believed to have a similar effect on PSA levels in both the bladder and the prostate. To assess the effects of tadalafil on PSA levels in the rat, we administered tadalafil or a tadalafil-based treatment of the rat, which was administered the same dosage of tadalafil as the rat. In the rat, we found that tadalafil increased PSA levels by 1.6-fold and PSA levels by 0.8-fold in the rat, respectively. These results suggested that tadalafil may inhibit PSA and PSA-related factors in the rat, which may be used to treat prostate-specific antigen (PSA) levels in patients with benign prostatic hyperplasia. Tadalafil can improve PSA levels in the rat by decreasing the PSA concentration in the prostate.
1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).
2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.
3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.
Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:
1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).
2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.
3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.
Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:
| interaction name | value |
|---|---|
| Cialis (tadalafil) | |
| e.g. |
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